Please follow these instructions to properly setup Dr.Explain on your PC. It's easy.
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Extract setup.exe from the downloaded archive. Use WinZip or another un-ZIP software.
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No uninstallation of a previous version is required.
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Run setup.exe and follow the instructions. If you need to create PDF files within the Dr.Explain then you'll be offered to install Java Run-Time Environment.
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Run the Dr.Explain once the installation is finished.